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Reithmann, C., Reber, D., Kozlik-Feldmann, R., et al. (1997) A post-receptor defect of adenylyl cyclase in severely failing myocardium from children with congenital heart disease. European Journal of Pharmacology, 330, 79-86.

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• TITLE: First Results of ACH Cardioplegic Solution Clinical Application in Newborns and Infants under One Year of Age

  AUTHORS: L. A. Bockeria, A. A. Boldyrev, O. I. Kulaga, G. A. Blejyants, D. N. Egorov, A. E. Popov, K. V. Mumladze, I. F. Egorova, T. V. Artuhina, N. V. Kalaeva, R. R. Movsesian

  KEYWORDS: Cardioplegic Solution Natural Dipeptides; Cardioplegic Ischemia; Immature Myocardium

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.3 No.5A, August 23, 2013

  ABSTRACT: Study objective involved comparison of two cardioplegic solutions: HTK-solution possessing high buffer capacity and a new ACH-solution with aminoacid buffer. Results revealed high cardioprotective efficiency during surgical repair of complex congenital heart disease both in the group that had received Custodiol and in the group that had received ACH-solution. Clinical and morphological parameters demonstrate high level of myocardial protection from intraoperative ischemia for single usage of ACH-solution during cardioplegic ischemia under 60 minutes in duration.