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A. M. Burja, H. Radianingtyas, A. Windust and C. J. Barrow, “Isolation and Characterization of Polyunsatu rated Fatty Acid Producing Thraustochytrium Species: Screening of Strains and Optimization of Omega-3 Pro duction,” Applied Microbiology and Biotechnology, Vol. 72, No. 6, 2003, pp. 1161-1169. doi:10.1007/s00253-006-0419-1

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• TITLE: Large-Scale Production of Microalgal Lipids Containing High Levels of Docosahexaenoic Acid upon Fermentation of Aurantiochytrium sp. KRS101

  AUTHORS: Won-Kyung Hong, Anna Yu, Baek-Rock Oh, Jang Min Park, Chul Ho Kim, Jung-Hoon Sohn, Akihiko Kondo, Jeong-Woo Seo

  KEYWORDS: Aurantiochytrium sp.; Heterotrophic Microalga; Large-Scale Cultivation; Lipid; Docosahexaenoic Acid

  JOURNAL NAME: Food and Nutrition Sciences, Vol.4 No.9A, August 21, 2013

  ABSTRACT: In this study, large-scale production of microalgal lipid containing high levels of docosahexaenoic acid (DHA) by fermentation of Aurantiochytrium sp. KRS101 was performed. The microalgal strain yielded productivity of docosahex-aenoic acid (DHA) productivity of 1.08 and 1.6 g/L/d by fermentation at 300-L and 5000-L scale stirrer-type bioreactor. The productivity was significantly enhanced upto 5.6 g/L/d by fermentation at 6000-L scale airlift-type bioreactor, probably due to the reduced shearing force. The microalgal lipid could be efficiently recovered by safe extraction methods such as ethanol extraction, hot water extraction or supercritical fluid extraction, promising commercial potential of the microalgal DHA-rich lipid in the food and feed industry.