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Li, Y., Gor, D., Walicki, D., Jenny, D., Jones, D., Barbour, P. and Castaldo, J. (2012) Spectrum and potential pathogenesis of reversible posterior leukoencephalopathy syndrome. Journal of Stroke and Cerebrovascular Diseases, 21, 873-882. doi:10.1016/j.jstrokecerebrovasdis.2011.05.010

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• TITLE: Posterior reversible encephalopathy syndrome induced after blood transfusion for severe anemia

  AUTHORS: Kei-ichiro Wada, Masayoshi Kano, Yutaka Machida, Nobutaka Hattori, Hideto Miwa

  KEYWORDS: Posterior Reversible Encephalopathy Syndrome; Anemia; Blood Transfusion

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.2 No.5, August 16, 2013

  ABSTRACT: Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological syndrome characterized by headache, confusion, seizures, and cortical visual loss, as well as subcortical edema without infarction on neuroimaging. We report a 56-year-old woman who developed typical manifestations of PRES, 6 days after blood transfusion for severe anemia. Acute volume overloads by transfusion may exceed the capacity of autoregulation of perfusion pressure, possibly resulting in vasogenic edema. We propose that it is clinically important to recognize that rapid correction of anemia by blood transfusion may carry the risk of inducing PRES.