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Soslowsky, L.J., Thomopoulos, S., Esmail, A., Flanagan, C.L., Iannotti, J.P., Williamson, J.D. and Carpenter, J.E. (2002) Rotator cuff tendinosis in an animal model: Role of extrinsic and overuse factors. Annual Review of Biomedical Engineering, 30, 1057-1063.

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• TITLE: Mesenchymal stem cells for the treatment of tendon disorders

  AUTHORS: Lucia Machová Urdzíková, Petr Lesný, Eva Syková, Pavla Jendelová

  KEYWORDS: Tendinophaty; Tendinosis; Tendonitis; Models of Tendon Injuries; Mesenchymal Stem Cells; Rotator Cuff; Achilles Tendon; Tendon Rupture

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.6 No.8A, August 16, 2013

  ABSTRACT: Tendon disorders are associated with increased morbidity and a reduction in the quality of life, especially in people of working age. Recently, a new approach, cell-based therapy, offers promising potential to treat tendon injuries. Mesenchymal stem cells are the most suitable candidates for such therapies due to their capacity to differentiate into cells of mesodermal origin, their paracrine properties and their potential use in autologous transplantation. This review summarizes experimental as well as clinical data focusing on the use of mesenchymal stem cells to treat tendinophaties.