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Borst, J.G. and de Vries, L.A. (1950) The three types of “natural” diuresis. Lancet, 2, 1-6. doi:10.1016/S0140-6736(50)91818-6

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• TITLE: Comparison between different methods of urine collection for estimation of albumin-creatinine ratio in patients with type-2 diabetes mellitus

  AUTHORS: Subinay Datta, Mrinal Pal

  KEYWORDS: Microalbuminuria; Albumin-Creatinine Ratio; Diabetic Nephropathy

  JOURNAL NAME: Advances in Biological Chemistry, Vol.3 No.4, August 9, 2013

  ABSTRACT: In patients with diabetes mellitus, urinary albumin-creatinine-ratio (ACR) predicts progressive kidney disease. In order to determine the better urine sample for detecting ACR, we estimated ACR in three modes of urine sample. Two hundred patients of uncontrolled diabetes mellitus with proteinuria irrespective of age and sex were studied for urinary ACR in all the three types of samples over a period of 2 years. The statistical analysis showed that first morning ACR (r = 0.999, p > 0.001) of the subjects was more significantly correlated with their 24 hour urine sample ACR than spot urine (r = 0.995, p