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Lee, K.C., Su, W.P. and Muller, S.A., (1990) Multicentric cloacogenic carcinoma: Report of a case with anogenital pruritus at presentation. Journal of American Academy of Dermatology, 23, 1005-1008. doi:10.1016/0190-9622(90)70323-A

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• TITLE: Unusually aggressive primary cloacogenic carcinoma of the vulva: A case report and literature review

  AUTHORS: Rajni Chibbar, Kimberly A. Wood, Christopher K. Giede, Anita Agrawal

  KEYWORDS: Cloacogenic Vulvar Cancer; Metastasis

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.2 No.5, August 8, 2013

  ABSTRACT: Vulvar cancer is an uncommon tumor and represents 3%-5% of all female genital tract malignancies. The overall incidence is 1.5/100,000 women. Histopathologically the vast majority (90%) are squamous cell carcinomas. Primary cloacogenic carcinoma of the vulva is extremely rare with less than 20 cases reported in English literature [1]. These tumors are thought to arise from embryonic or ectopic rests of cloacogenic tissue. The majority of these reported cases is relatively indolent cancer, only one case of cloacogenic carcinoma of the vulva reported metastatic spread to the inguinal lymph nodes and none that describe distant metastases. Here we present an aggressive and diagnostically challenging case of cloacogenic carcinoma of the vulva and a review of current literature to date.