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Moustafa, R.R., Momjian-Mayor, I., Simon Jones, P., Morbelli, S., Day, D.J., Aigbirhio, F.I., Fryer, T.D., Warburton, E.A. and Baron, J.C. (2011) Microembolism versus hemodynamic impairment in rosary-like deep watershed infarcts: A combined positron emission tomography and transcranial doppler study. Stroke, 42, 3138-3143. doi:10.1161/STROKEAHA.111.616334

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• TITLE: Possibilities of transcatheter treatment of patients after extensive ischemic stroke

  AUTHORS: Ivan V. Maksimovich

  KEYWORDS: Extensive Ischemic Stroke; Neurological Deficits; Post-Stroke Dementia; Transcatheter Treatment; Laser Revascularization

  JOURNAL NAME: World Journal of Neuroscience, Vol.3 No.3, July 22, 2013

  ABSTRACT: The research investigates the efficacy of brain transcatheter laser revascularization in patients who have had extensive ischemic stroke. 1125 patients aged 29 - 81 (average age 75) with cerebral atherosclerosis were examined. The examination plan included: CT brain scan, magnetic resonance imaging (MRI), brain scintigraphy (SG), rheoencephalography (REG), cerebral multi-gated angiography (MUGA), laboratory tests, assessment of severity of dementia (CDR), cognitive impairment (MMSE) and activities of daily living (IB). 93 patients suffered extensive ischemic stroke of whom 7 (7.53%) had 10 - 15 IB points, 25 (26.88%)—20 - 30 IB points, 61 (65.59%)—35 - 45 IB points. 69 patients underwent transcatheter treatment (Test Group). 24 patients underwent conservative treatment (Control Group). High-energy laser systems were used for revascularization of major intracranial arteries; lowenergy laser systems were used for revascularization of distal intracranial branches. Test Group: 67 (97.10%) patients had good immediate angiographic outcome manifested in the restoration of lumen and patency of the affected vessels as well as in collateral revascularization. 12 - 24 months later the following positive trend was observed: 14 (20.59%) patients demonstrated good clinical outcome (IB 90 - 100); 26 (38.24%) patients had satisfactory clinical outcome (IB 75 - 85); 28 (41.18%) patients showed relatively satisfactory clinical outcome (IB 60 - 70); relatively positive clinical outcome (IB satisfactory clinical outcome (IB 60 - 70), relatively positive clinical outcome (IB causes regression of mental, intellectual and motor disorders, promotes regression of post-stroke dementia and significantly improves the quality of life, which makes it noticeably different from the conservative methods of treatment.