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Alonso-Frech, F., Zamarbide, I., Alegre, M., Rodríguez-Oroz, M.C., Guridi, J., Manrique, M., Valencia, M., Artieda, J. and Obeso, J.A. (2006) Slow oscillatory activity and levodopa-induced dyskinesias in Parkinson’s disease. Brain, 129, 1748-1757. doi:10.1093/brain/awl103

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• TITLE: The contribution of functional neurosurgery to the understanding of the physiopathology of Parkinson’s disease

  AUTHORS: Juan Antonio Barcia, Fernando Alonso-Frech

  KEYWORDS: Parkinson’s Disease; Functional Neurosurgery; Oscillatory Activity

  JOURNAL NAME: Advances in Parkinson's Disease, Vol.2 No.3, July 22, 2013

  ABSTRACT: Functional neurosurgery is nowadays a recognized treatment for advanced Parkinson’s disease with pharmacologically uncontrolled symptoms. This procedure brings us the unique opportunity to deepen in the knowledge of PD’s physiopathology by recording patients’ neural activity, and possibly in the future it will let us select the appropriate target and the optimal chronic stimulation pattern.