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L. G. Brito, J. M. de Andrade, T. Lins-Almeida, F. E. Zola, M. N. Pinheiro, H. R. Marana, D. G. Tiezzi and F. M. Peria, “Safety and Efficacy of Gemcitabine plus Cisplatin Combination in Pretreated Metastatic Breast Cancer Patients,” Medical Oncology, Vol. 29, No. 1, 2012, pp. 33-38. doi:10.1007/s12032-010-9793-8

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• TITLE: Management of the Case of a Young Female Patient with Multiple Malignancies and Germline R24P CDKN2A Gene Mutation

  AUTHORS: Gabriella Uhercsák, Ágnes Dobi, Roland Gyulai, Judit Oláh, László Kaizer, Katalin Ormándi, Adrienne Cserháti, György Lázár, Gyula Farkas, Zsuzsanna Kahán

  KEYWORDS: Breast Cancer; Melanoma; Pancreatic Cancer; R24P CDKN2A Gene Mutation

  JOURNAL NAME: Journal of Cancer Therapy, Vol.4 No.7A, July 17, 2013

  ABSTRACT: The case of a young female patient with metachronous primary melanomas, advanced breast and pancreatic cancers is reported. The 5 different tumors diagnosed within six years, were managed with curative intent. Genetic analysis revealed the mutation of the R24P CDKN2A gene in a heterozygote form in both the patient and her father. Careful tertiary prevention during the follow-up of the patient is needed.