TITLE:
Management of the Case of a Young Female Patient with Multiple Malignancies and Germline R24P CDKN2A Gene Mutation
AUTHORS:
Gabriella Uhercsák, Ágnes Dobi, Roland Gyulai, Judit Oláh, László Kaizer, Katalin Ormándi, Adrienne Cserháti, György Lázár, Gyula Farkas, Zsuzsanna Kahán
KEYWORDS:
Breast Cancer; Melanoma; Pancreatic Cancer; R24P CDKN2A Gene Mutation
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.4 No.7A,
July
17,
2013
ABSTRACT: The case of a young female patient
with metachronous primary melanomas, advanced breast and pancreatic cancers is
reported. The 5 different tumors diagnosed within six years, were managed with
curative intent. Genetic analysis revealed the mutation of the R24P CDKN2A gene in a heterozygote form in
both the patient and her father. Careful tertiary prevention during the follow-up of
the patient is needed.