TITLE:
Synthesis and Characterization of Some New Cationic Derivatives of Biological Interest
AUTHORS:
Moshera Z. Mohamed, Samar A. Abubshait, Eqbal J. Bushlaibi
KEYWORDS:
Quaternary Ammonium Amphiphiles; Micellization; Adsorption; Surface Properties; Biological Activity of Quaternized
JOURNAL NAME:
Journal of Surface Engineered Materials and Advanced Technology,
Vol.3 No.3,
July
12,
2013
ABSTRACT: A homologous series of cationic
surfactants were synthesized and characterized by spectral studies, mass, IR, 1H
NMR, 13C NMR, 2D NMR and elemental analysis. The surface activities
of these amphiphiles were measured, including surface tension (γ), critical micelle concentration
(CMC), effectiveness (pcmc), efficiency (PC20), maximum surface
excess (Γmax) and minimum
surface area (Amin) at 25℃. Adsorption and micellization free
energies of these amphiphiles in their solutions showed a good tendency towards
adsorption at the interfaces. The synthesized amphiphiles showed good antimicrobial
activity.