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Brummel, K.E., Paradis, S.G., Butenas, S. and Mann, K.G. (2002) Thrombin functions during tissue factor-induced blood coagulation. Blood, 100, 148-152. doi:10.1182/blood.V100.1.148

has been cited by the following article:

• TITLE: Laser induced clot formation in blood treated by EDTA

  AUTHORS: Balsam M. Mirdan

  KEYWORDS: 980 nm Laser; Blood Clot; Laser Tissue Interaction; Photochemical Interaction

  JOURNAL NAME: Natural Science, Vol.5 No.7, July 9, 2013

  ABSTRACT: Patients under systemic (ethylenediaminetetraacetic acid) EDTA are at risk of hemorrhage for any accidental trauma even the superficial ones. This research is a trial to use 980 nm wavelength laser light to provide coagulation for such patients in a local region without collateral thermal damage. Material and Method: 980 nm Diode laser operating in a continuous mode (CW) was incident on human blood treated with EDTA inDurhamtubes. The used parameters were (2.25, 3, 3.75 and 6.75) W output power for variable exposure times (1, 3, 9 and 27) s. Results: A homogenous clot was performed at 4327.84 J/cm2 deposited energy density with the absence of any thermal stress in the blood. Conclusion: 980 nm laser wavelength provides a local photochemical bond break of the anticoagulant enhancing blood coagulation for medically compromised patients.