TITLE:
Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China
AUTHORS:
Guohong Tian, Lin Sun, Yunhong He, Xiaojun Zhang
KEYWORDS:
Creutzfeldt-Jakob Disease; Visual Disturbance; Heidenhain Variant; Diffusion Weighted Imaging
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.4 No.7,
July
4,
2013
ABSTRACT: Creutzfeldt-Jakob disease (CJD) is a rare but fatal neurodegenerative prion disease. Classic CJD comprises a clinical triad of rapidly progressive dementia, myoclonus, and EEG abnormality. At initial presentation, this classic triad is present only in a minority of cases. Visual impairment is one of the predominant manifestations in the course of CJD, especially in Heidenhain variant phenotype. We reported a case presenting with progressive blurred vision, along with other neurological symptoms, who diagnosed as sporadic CJD with cortical blindness in China.