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Chu, T.C., Lee, L.H., Gaynor, J.J., Vega, Q.C., Lustigman, B.K. and Srinivasan, S. (2007) Identification of the Synechococcus sp. IU 625 metallothionein gene and its evolutionary relationship to the metallothionein gene of other Cyanobacteria. In: Proceeding of the 2007 International Conference on Bioinformatics & Computational Biology. CSREA Press, 201-207.

has been cited by the following article:

• TITLE: Physiological effects of nickel chloride on the freshwater cyanobacterium Synechococcus sp. IU 625

  AUTHORS: Brian Nohomovich, Bao T. Nguyen, Michael Quintanilla, Lee H. Lee, Sean R. Murray, Tin-Chun Chu

  KEYWORDS: Harmful Algal Blooms (HABs);Cyanobacteria; Nickel Chloride; Stress Response; ICP-MS

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.4 No.7B, July 4, 2013

  ABSTRACT: Harmful algal blooms (HABs) are a serious environmental problem globally. The ability of cyanobacteria, one of the major causative agents of HABs, to grow in heavy metal polluted areas is proving a challenge to environmental restoration initiatives. Some cyanobacteria secrete toxins, such as microcystin, that are potentially dangerous to animals and humans. In this study, the physiology of a cyanobacterium was assessed to nickel chloride exposure. Cell growths were monitored throughout the study with various nickel chloride concentrations (0, 10, 25 or 50 mg/L). Morphological abnormalities were observed with microscopic image analyses. Inductively coupled plasma mass spectrometry (ICP-MS) was carried out to trace the distribution of nickel during the growth period. This study provides insight on potential nickel response mechanisms in freshwater cyanobacteria, which may lead to effective HAB prevention strategy development.