TITLE:
A case of endometrial cancer presenting with malignant spinal cord compression
AUTHORS:
Shigeki Taga, Mari Sawada, Aya Nagai, Dan Yamamoto, Ryoji Hayase
KEYWORDS:
Malignant Spinal Cord Compression; Endometrial Cancer
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.3 No.5,
July
2,
2013
ABSTRACT: Malignant spinal cord
compression (MSCC) rarely presents in patients with endometrial cancer. It usually occurs months or years after the diagnosis of the primary tumor. A 65-year-old
woman presented with a huge uterine tumor suspecting leiomyosarcoma. She
underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Histopathological
examination revealed mixed carcinoma (small cell carcinoma and endometrioid
adenocarcinoma) of the endometrium. She presented with upper abdominal pain,
back pain, cystoplegia and paraplegia of lower extremities postoperatively.
Magnetic resonance imaging revealed bone metastasis with destruction of the
eighth thoracic vertebral body as the sites of metastasis. Vertebrectomy and
irradiation therapy were performed for the lesion. Although she received systemic
chemotherapy consisting of paclitaxel and carboplatin, she died 4 months
after hysterectomy.