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C. N. Suh, H. Y. Chun, Y. M. Ye, et al., “Unresponsiveness of C-Reactive Protein in the Non Infectious Inflammation of Systemic Lupus Erythematosus Is Associated with Interleukin 6,” Clinical Immunology, Vol. 119, No. 3, 2006, pp. 291-296. doi:10.1016/j.clim.2005.11.006

has been cited by the following article:

• TITLE: Discordantly Elevated Erythrocyte Sedimentation Rate (ESR) and Depressed C-Reactive Protein (CRP) Values in Early Diagnosis of Pulmonary Tuberculosis Patients in Maiduguri, Nigeria

  AUTHORS: Zaccheaus Awortu Jeremiah, Iruoma Leonard, Anthony C. Ezinma

  KEYWORDS: Erythrocyte Sedimentation Rate; C-Reactive Protein; Pulmonary Tuberculosis

  JOURNAL NAME: Open Journal of Blood Diseases, Vol.3 No.2, June 25, 2013

  ABSTRACT: Background: ESR and CRP measurements reflect different aspects of systemic inflammation. Generally, they are either elevated or depressed at the same time. This study was aimed at evaluating the clinical ability of these markers in the early diagnosis of pulmonary tuberculosis. Materials and Methods: A total of 50 (male 39, female 21) patients who tested positive to Acid Alcohol Fast Bacilli (AAFB) were studied. ESR and CRP values were estimated using standard procedures. Results: The mean ESR value among the AAFB positive patients was 53.16 ± 4.92 mm/hr while the CRP value was 0.273 ± 0.035 mg/L. Gender and age were not found to have any influence on the ESR and CRP values. No relationship was found to exist between ESR and CRP (r = 0.17; p = 0.235) and age (r = 0.125; p = 0.388). Conclusion: A moderately elevated ESR and low CRP values exist at the early diagnosis of tuberculosis. There is no correlation between ESR and CRP at the onset of tuberculosis; hence CRP cannot be used as a screening tool for early diagnosis of tuberculosis.