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J. H. Shen, X. Y. Xu, F. Cheng, et al., “Virtual Screening on Natural Products for Discovering Active Compounds and Target Information,” Current Medicinal Chemistry, Vol. 10, No. 21, 2003, pp. 2327-2342. doi:10.2174/0929867033456729

has been cited by the following article:

• TITLE: The Success of Natural Products in Drug Discovery

  AUTHORS: Mouhssen Lahlou

  KEYWORDS: Biodiversity; Drug Discovery; Efficacy; Natural Products; New Technologies; Structural and Chemical Diversity; Success Steps

  JOURNAL NAME: Pharmacology & Pharmacy, Vol.4 No.3A, June 24, 2013

  ABSTRACT: Drug discovery leading to robust and viable lead candidates’ remains a challenging scientific task, which is the transition from a screening hit to a drug candidate, requires expertise and experience. Natural products and their derivatives have been recognized for many years as a source of therapeutic agents and of structural diversity. However, in addition to their chemical structure diversity and their biodiversity, the development of new technologies has revolutionized the screening of natural products in discovering new drugs. Applying these technologies compensates for the inherent limitations of natural products and offers a unique opportunity to re-establish natural products as a major source for drug discovery. The present article attempts to describe the utilization of compounds derived from natural resources as drug candidates, with a focus on the success of these resources in the process of finding and discovering new and effective drug compounds, an approach commonly referred to as “natural product drug discovery”.