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Pidaparti, R.M.V., Chandran, A., Takano, Y. and Turner, C.H. (1996) Bone mineral lies mainly outside collagen fibrils: Predictions of a composite model for osteonal bone. Journal of Biomechanics, 29, 909-916. doi:10.1016/0021-9290(95)00147-6

has been cited by the following article:

• TITLE: Effect of off-axis cell orientation on mechanical properties in smooth muscle tissue

  AUTHORS: P. A. Sarma, Ramana M. Pidaparti, Richard A. Meiss

  KEYWORDS: Smooth Muscle; Shear Stress; Finite Element Model; Cell Orientation; Shortening Strain

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.4 No.1, January 29, 2011

  ABSTRACT: The cell alignment in a smooth muscle tissue plays a significant role in determining its mechanical proper-ties. The off-axis cell orientation θ” not only effects the shortening strain but also modifies the shear stress relationship significantly. Both experiments and finite element analysis were carried out on a tracheal smooth muscle strip to study how the cell alignment in smooth muscle affects the shear stiffness and shear stresses as well as deformation. A simple model for shear stiffness is derived using the data from experiments. Shear stiffness results obtained from the model indicate that the muscle shear stiff-ness values increase non-linearly with strain and with higher off-axis alignment of cells. Results of deforma-tion and shear stresses obtained from finite element analsysis indicate that the maximum shear stress values of tracheal smooth muscle tissue at 45% of strain are 2.5 times the corresponding values at 20% of strain for all three off-axis cell orientation values θ = 15?, 30? and 45?.