Article citationsMore>>

S. Khabnadideh, Z. Rezaei, A. Khalafi-Nezhad, R. Bahrinajafi, R. Mahamadi and A. A. Farrokhroz, “Synthesis of N-Alkylated Derivatives of Imidazole as Antibacterial Agents,” Bioorganic & Medicinal Chemistry Letters, Vol. 13, No. 17, 2003, pp. 2863-2865. doi:10.1016/S0960-894X(03)00591-2

has been cited by the following article:

• TITLE: [1-(4-Nitrobenzyl)-2-butyl-4-chloro-1H-imidazol-5-yl]-4, 5-dihydro-1-phenyl-1H-pyrazole: Synthesis, Anti-Inflammatory and Analgesic Activities

  AUTHORS: S. Sreenivasa, B. J. Shankar

  KEYWORDS: Anti-Inflammatory; Analgesic; N-(nitrobenzyl)-imidazole aldehyde; Chloramine-T

  JOURNAL NAME: Open Journal of Medicinal Chemistry, Vol.3 No.2, June 20, 2013

  ABSTRACT: In the present investigation, series of Bis (heterocycle)s bearing pyrazoline in combination of the imidazole derivatives have been synthesized via 1,3-dipolar cycloaddition reactions of N-(nitrobenzyl)-imidazole nitrile imines with different dipolarophiles. All the newly synthesized compounds were characterized and screened for analgesic-anti-inflammatory activities and were compared with the standard drugs. The compounds exhibited excellent anti-inflammatory and analgesic activities. Out of the compounds studied 4b, 4d and 4g compounds shown statistically significant activity comparable to the standard drugs Ibuprofen and Aspirin at the same dose.