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Liu, R.H., Mizuta, M., Kurose, T. and Matsukura, S. (2002) Early events involved in the development of insulin resistance in zuker fatty rats. International Journal of Obesity, 26, 318-326. doi:10.1038/sj.ijo.0801924

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• TITLE: One-time injection of calcitonin induces glucose intolerance in children with the first degree obesity

  AUTHORS: S. S. Moisa, A. D. Nozdrachev

  KEYWORDS: Calcitonin; Obesity; Carbohydrate Metabolism; Hyperglycemia; Glucose-Intolerance

  JOURNAL NAME: Health, Vol.5 No.6A, June 17, 2013

  ABSTRACT: The effect of calcitonin on the blood glucose level in glucose-tolerance test of children with the first degree obesity was studied. Initial blood glucose level was normal and glucose-tolerance test per os didn’t expose glucose tolerance impairment in children under control. Calcitonin didn’t change initial glucose concentration but evoked impairment of glucose tolerance. The girls with the first degree obesity were more sensitive to hyperglycemic effect of calcitonin than the boys. Sex specificities must be taken into consideration in calcitonin treatment. Besides one ought mean that the increasing secretion of calcitonin occurs in stress-reactions. In these conditions endogenous calcitonin can make the same effect on the regulation of carbohydrate metabolism as exogenous injections of hormone.