TITLE:
One-time injection of calcitonin induces glucose intolerance in children with the first degree obesity
AUTHORS:
S. S. Moisa, A. D. Nozdrachev
KEYWORDS:
Calcitonin; Obesity; Carbohydrate Metabolism; Hyperglycemia; Glucose-Intolerance
JOURNAL NAME:
Health,
Vol.5 No.6A,
June
17,
2013
ABSTRACT: The effect of calcitonin on the
blood glucose level in glucose-tolerance test of children with the first degree
obesity was studied. Initial blood glucose level was normal and glucose-tolerance
test per os didn’t expose glucose
tolerance impairment in children under control. Calcitonin didn’t change
initial glucose concentration but evoked impairment of glucose tolerance. The
girls with the first degree obesity were more sensitive to hyperglycemic
effect of calcitonin than the boys. Sex specificities must be taken into
consideration in calcitonin treatment. Besides one ought mean that the
increasing secretion of calcitonin occurs in stress-reactions. In these
conditions endogenous calcitonin can make the same effect on the regulation of
carbohydrate metabolism as exogenous injections of hormone.