TITLE:
Modelling One-Pot Method for Synthesis of 2,3-Dihydro-1H-pyrrolo[2,1-c][1,4]benzothiazine 5,5-Dioxides and Their Homologues
AUTHORS:
Oleksandr Yu Grevtsov, Oleg V. Zaremba, Anna B. Bondarenko, Oleksandr G. Drushlyak, Sergiy M. Kovalenko, Valentyn P. Chernykh
KEYWORDS:
Sulfones; Lactims; Cyclization; Heterocycles; Nucleophilic Aromatic Substitution
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.3 No.2,
June
14,
2013
ABSTRACT: A facile
method for synthesis of 2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzothiazines by interaction of
methylenactive (2-fluorophenyl)sulfones with homologues of either
5-methoxy-3,4-dihydro-2H-pyrrole or
5-(methylthio)-3,4-dihydro- 2H-pyrrole has been developed.