TITLE:
Time-Effect Relationship of Toxicity Induced by Roundup® and Its Main Constituents in Liver of Carassius Auratus
AUTHORS:
Jinyu Fan, Jinju Geng, Hongqiang Ren, Xiaorong Wang
KEYWORDS:
Carassius Auratus; Roundup®; Hydroxyl Radical (·OH); Toxicity
JOURNAL NAME:
Computational Water, Energy, and Environmental Engineering,
Vol.2 No.2B,
June
11,
2013
ABSTRACT: In order to evaluate the eco-toxicological effects of Roundup® on Carassius auratus (C. auratus), fish were exposed to 32 μg/L Roundup®, isopropylamine salt of glyphosate (G.I.S) and polyoxyethylene amine (POEA) over different periods (0.5, 1, 3, 7 and 14 d). Hydroxyl radical (·OH), malondialdehyde (MDA) and acetylcholinesterase (AChE) in liver were detected in this study. Results showed that the generation of ·OH increased before 7 d, but without significantly difference. ·OH was induced at 1 d for POEA group, 3 d for Roundup® group and 7 d for G.I.S group. At 14 d, ·OH generation returned to normal levels. MDA contents all increased significantly (p