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E. Sancho, J. J. Cerón and M. D. Ferrando, “Cholinesterase Activity and He-matological Parameters as Biomarkers of Sublethal Mo-linate Exposure in Anguilla Anguilla,” Ecotoxicology and Environmental Safety, Vol. 46, No. 1, 2000, pp. 81–86. doi:10.1006/eesa.1999.1888

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• TITLE: Time-Effect Relationship of Toxicity Induced by Roundup® and Its Main Constituents in Liver of Carassius Auratus

  AUTHORS: Jinyu Fan, Jinju Geng, Hongqiang Ren, Xiaorong Wang

  KEYWORDS: Carassius Auratus; Roundup®; Hydroxyl Radical (·OH); Toxicity

  JOURNAL NAME: Computational Water, Energy, and Environmental Engineering, Vol.2 No.2B, June 11, 2013

  ABSTRACT: In order to evaluate the eco-toxicological effects of Roundup® on Carassius auratus (C. auratus), fish were exposed to 32 μg/L Roundup®, isopropylamine salt of glyphosate (G.I.S) and polyoxyethylene amine (POEA) over different periods (0.5, 1, 3, 7 and 14 d). Hydroxyl radical (·OH), malondialdehyde (MDA) and acetylcholinesterase (AChE) in liver were detected in this study. Results showed that the generation of ·OH increased before 7 d, but without significantly difference. ·OH was induced at 1 d for POEA group, 3 d for Roundup® group and 7 d for G.I.S group. At 14 d, ·OH generation returned to normal levels. MDA contents all increased significantly (p