TITLE:
Antiproliferative Activity of “Lycopersicon esculentum” Leaves (Var. Paul Robenson): Preliminary Study
AUTHORS:
Carmela Saturnino, Annalisa Spagnuolo, Chiara Palladino, Ada Popolo, Giuseppina Tommonaro, Rocco De Prisco, Aldo Pinto
KEYWORDS:
Lycopersicon esculentum; Antiproliferative Activity; Glioma Cell Line
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.4 No.6,
June
7,
2013
ABSTRACT: Among plants, the Lycopersicon esculentum (Solanaceae) is the most important for its beneficial effects on health. Several epidemiological studies have shown the benefits of tomato consumption in the cancer and cardiovascular disease prevention. Tomato products constitute the major source of lycopene, the most potent antioxidant among carotenoids in vitro. In tomatoes leaves are also present many secondary metabolites including phenolic compounds, phytoalexins, protease inhibitors and glycoalkaloids who protect against adverse effects of hosts including fungi, bacteria, viruses, and insects and are involved in host-plant resistance. In this work we evaluated the antiproliferative activity of tomato leaves extract (var. Paul Robenson) in vitro.