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M. Giersiepen, L. J. Wurzinger, R. Opitz and H. Reul, “Estimation of Shear Stress-Related Blood Damage in Heart Valve Prostheses—In Vitro Comparison of 25 Aortic Valves,” The International Journal of Artificial Organs, Vol. 13, No. 5, 1990, pp. 300-306.

has been cited by the following article:

• TITLE: Dynamic Simulation and Hemolysis Evaluation of the Regurgitant Flow over a Tilting-Disc Mechanical Heart Valve in Pulsatile Flow

  AUTHORS: Uzu-Kuei Hsu, Pong-Jeu Lu

  KEYWORDS: Heart Valve; CFD; Blood Cell Damage Index; Stress; Lagrangian Particle Tracking

  JOURNAL NAME: World Journal of Mechanics, Vol.3 No.3, June 4, 2013

  ABSTRACT: Regurgitation in the heart diastolic phase represents a critical flow condition associated with many heart valve design considerations. The finite volume method, the Low-Reynolds-Number k-ω turbulent model and sliding mesh model are employed to solve and compare the complex flow field and the torque in each case. The end results expected from a cardiovascular CFD analysis are not limited only to the flowfield investigations. More importantly, it needs an evaluation criterion to judge if the design is acceptable as considered from a broader blood cell damage or activation perspective. In this study, blood cell damage index developed based on stress-time empirical rule and Lagrangian particle tracking is introduced to assess the viscous and turbulence-induced stresses effect to the blood cells.