TITLE:
Thromboelastometry during Labor and after Delivery
AUTHORS:
Gabriele Tola, Silvia Sirparo, Luca Ruggeri, Giorgio Capogna
KEYWORDS:
Pregnancy; Labor; Thromboelastometry
JOURNAL NAME:
Open Journal of Anesthesiology,
Vol.3 No.4,
June
4,
2013
ABSTRACT: The normal values of
thromboelastometry (MonoTEM-A?, Framar Hemologix) in pregnancy have not been
determined. The aim of this study was to establish the reference ranges for the
thromboelastometer in healthy pregnant women during labor and after delivery. After ethical
institutional approval and informed consent, we collected blood samples for
analysis from 95 healthy labouring women and 40 volunteers (non pregnant women,
control group). A sample of 360 μL of whole native blood was tested using the
MonoTEM-A? equipment and analyzed within 4 min, at 37℃. We recorded: R = time to initial fibrin formation; K = time
to initial clot formation; Alpha Angle = acceleration of clot formation and MA = strength of the blood clot. When compared
to the control group, R and K values were lower in women during labor and after
the delivery. The Alpha angle and MA values were higher in the laboring women
and in the same women after delivery as compared to the control group. Our
study determined the reference ranges for the MonoTEM-A? in pregnancy during labor and immediately after the
delivery. Data obtained from thromboelastometry confirm the hypercoagulability
status in pregnancy and the puerperium. MonoTEM-A? thromboelastometry may be a very useful tool to assess the clotting activity in this
patient setting.