TITLE:
Myeloid sarcoma as a differential diagnosis of small bowel obstruction
AUTHORS:
Bastian Kettler, Mahmoud Abbas, Bastian Ringe, Lothar Hambach, Jürgen Klempnauer, Michael Winkler, Hans-Heinrich Kreipe, Nikos Emmanouilidis
KEYWORDS:
Myeloid Sarcoma; Small Bowel Obstruction
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.2 No.2,
May
24,
2013
ABSTRACT: We are presenting the case of a 42-year-old male patient, who was hospitalized due to an
acute small bowel obstruction caused by a tissue mass of the mesentery. The
patient reported that he had a history of a testicular tumour. For therapy of
intestinal obstruction as well as for diagnostic reasons we decided to perform an explorative laparotomy. On histopathological
examination the immunohistological staining was positive for myeloperoxidase
(MPO) and KP-1 (CD68). Staining was slightly positive for Bcl-2, CD117, CD34,
but negative for CD3, CD4, CD5, CD8, CD20, CD30, CD79, Bcl-6 and S-100. This
leads to the diagnosis of a myeloid sarcoma. After recovery from surgery and
chemotherapy, allogenic bone marrow transplantation was performed. Most intestinal obstructions are caused
by postoperative adhesions or hernias and only in rare cases caused by a
myeloid sarcoma.