TITLE:
Recurrent ameloblastoma of the mandible: Surgical seeding or metastasis of malignant ameloblastoma?
AUTHORS:
Christina Klee, Sven Lindskog, Jan-M. Hirsch, Andreas Thor
KEYWORDS:
Ameloblastoma; Surgical Seeding; Metastasis
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.2 No.2,
May
24,
2013
ABSTRACT: The controversy of surgical seeding or metastasis of a
recurrent ameloblastoma is discussed in this paper, where we present a case
with a history of 28 years since primary diagnosis including several tumor
removals and reconstructive events. 23 years after primary diagnosis, we
removed a metastasis from the neck with similar histological features as the
primary tumor and the following recurrences of the mandible. We argue that the
removed tumor in the neck most possibly has its origin in surgical seeding of
cells during earlier resection and reconstruction and not by common ways of
metastasis. The seeding of tumor cells during tumor surgery and metastasis rate
of malignant ameloblastoma is discussed and the literature in this area is reviewed
in the paper.