TITLE:
Antibiotic Resistance Pattern of Bacteria Isolated from Patients of Urinary Tract Infections in Iraq
AUTHORS:
Mohemid M. Al-Jebouri, Salih A. Mdish
KEYWORDS:
Antibiotic Resistance; UTI; Pathogens; Iraq
JOURNAL NAME:
Open Journal of Urology,
Vol.3 No.2,
May
22,
2013
ABSTRACT: Objectives: The main objective of this study
was to investigate the bacterial infections of urinary tract in patients with
urolithiasis. The patients were referred to and/or visiting the Urology
Department in Tikrit Teaching Hospital in Tikrit city. Methods: The present study was carried out from November 2011 until July 2012.
One hundred and sixty patients with urolithiasis were included in the present
study whose ages ranged from 12 to 70 years. Male to female ratio was almost
2:1. The control group consisted of two groups; group one consisted of 40 persons
(20 males and 20 females) who were selected randomly from Tikrit city during
the period of this study and they had no previous personal nor family history
of urolithiasis, while group two consist of 40 persons (20 males and 20 females) infected
with urinary tract infection. Urine culture was done for all the patients and
the control group. Results: Forty five percent (45/160) of
these had UTI’s. Six patients revealed mixed bacterial growth. Eighty-four
percent (38/45) of patients with UTI were infected with gram negative organisms
where as only 16% (7/45) of patients were infected with gram positive organisms.
The majority of the gram negative bacteria isolated belonged to the family Enterobacteriaceae particularly E. coli as it
was isolated from 14 (31%) cases. The urease producing bacteria were isolated
from 31 cases (50%). Conclusions: UTI’s in urolithiasis was more
frequent in females than males and the percentages were 28/45 and 17/45
respectively. The most effective antimicrobial agent was amikacin and the least
effective one was ampicillin, whereas ciprofloxacin, cefoxitin, levofloxacin, nitrofurantoin, nalidixic acid, chloramphenicol, amoxycillin and
gentamicin were effective at different levels.