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Iwata, B. A., Pace, G. M., Dorsey, M. F., Zarcone, J. R., Vollmer, T. R., Smith, R. G., et al. (1994). The functions of self-injurious behavior: An experimental-epidemiological analysis. Journal of Applied Behavior Analysis, 27, 215-240.

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• TITLE: Acquisition of Avoidance Responding in the Fmr1 Knockout Mouse

  AUTHORS: Maria G. Valdovinos, Kelly Ippolito, Lauren Nawrocki, Greg Woods, Craige C. Wrenn

  KEYWORDS: Fragile X Syndrome, Fmr1 Knockout, Active Avoidance

  JOURNAL NAME: Psychology, Vol.1 No.5, December 28, 2010

  ABSTRACT: Fragile X Syndrome (FXS) is the most common inherited cause of mental retardation. Much work has been done characterizing the behavioral phenotype of the animal model of FXS, the Fmr1 knockout mouse. However, very little literature exists on knockout performance in the active avoidance task. This study evaluated if Fmr1 knockouts differed from wild type littermates in avoidance acquisition. Data revealed no difference in acquisition between knockouts and wild types.