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Yablonskaya, S.V., Filinska, O.M., Ostrovskaya, G.V. and Rybalchenko, V.K. (2009) Evaluation of hepatotoxicity of new derivative maleimides with cytostatic activity and its effect on lipid peroxidation and antioxidant system in liver. Ukrainian Biochemical Journal, 81, 83-92.

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• TITLE: The activities of endothelial elastase and cathepsin G in rats at oxidative stress caused by heavy metals salts

  AUTHORS: Nickolaj F. Starodub, Ljubov M. Samokhina

  KEYWORDS: Endothelial Elastase; Cathepsin G; Cobalt Chloride; Mercury Chloride; Rats

  JOURNAL NAME: Advances in Biological Chemistry, Vol.3 No.2, April 30, 2013

  ABSTRACT: CoCl2 introduction increased cathepsin G activity in the heart and liver as well as endothelial elastase (EEl) in kidney that indicated the development of destructive processes. CoCl2 introduction decreased EEl and cathepsin G activities in blood serum and cathepsin G in lungs. HgCl2 injection decreased EEl in blood serum, heart, liver, kidney and cathepsin G in blood serum. These decreasing of proteinases activities may be caused by cytotoxic effects of heavy metals and/or the inclusion of these proteases in the destructive processes and absence of their synthesis and/or release.