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Azevedo, B.F., Futuro, Neto Hde, A., Stefanon, I. and Vassallo, D.V. (2011) Acute cardiorespiratory effects of intracisternal injections of mercuric chloride. Neurotoxicology, 32, 350-354. doi:10.1016/j.neuro.2011.02.006

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• TITLE: The activities of endothelial elastase and cathepsin G in rats at oxidative stress caused by heavy metals salts

  AUTHORS: Nickolaj F. Starodub, Ljubov M. Samokhina

  KEYWORDS: Endothelial Elastase; Cathepsin G; Cobalt Chloride; Mercury Chloride; Rats

  JOURNAL NAME: Advances in Biological Chemistry, Vol.3 No.2, April 30, 2013

  ABSTRACT: CoCl2 introduction increased cathepsin G activity in the heart and liver as well as endothelial elastase (EEl) in kidney that indicated the development of destructive processes. CoCl2 introduction decreased EEl and cathepsin G activities in blood serum and cathepsin G in lungs. HgCl2 injection decreased EEl in blood serum, heart, liver, kidney and cathepsin G in blood serum. These decreasing of proteinases activities may be caused by cytotoxic effects of heavy metals and/or the inclusion of these proteases in the destructive processes and absence of their synthesis and/or release.