TITLE:
A Case Report of a Sarcomatoid Carcinoma Arising in the Renal Pelvis with Exuberant Osteosarcomatous Element
AUTHORS:
Hye In Ahn, Jongmin Sim, Hulin Han, Hyunsung Kim, Kijong Yi, Young Jin Jun, Abdul Rehman, Se Min Jang, Kiseok Jang, Seung Sam Paik
KEYWORDS:
Sarcomatoid Carcinoma; Osteosarcoma; Pelvis; Kidney
JOURNAL NAME:
Open Journal of Pathology,
Vol.3 No.2,
April
25,
2013
ABSTRACT: Sarcomatoid
carcinoma is a rare malignant tumor that has both malignant epithelial and
mesenchymal components. We describe a sarcomatoid carcinoma arising in the
right renal pelvis of a 68-year-old man. The dominant component of the tumor
was osteosarcomatous, but there were also focal carcinomatous areas. The
sarcomatous tumor cells produced abundant osteoid matrix surrounded by
osteoblastic cells. The carcinomatous tumor cells consisted of papillary urothelial
carcinoma. Immunohistochemical assay showed that the sarcomatous tumor cells
were positive for vimentin and negative for cytokeratin. The papillary
urothelial carcinoma was positive for cytokeratin and negative for vimentin. After
surgery, the patient underwent adjuvant chemotherapy. Four months later, he
presented with recurrence in the right subphrenic area and metastasis in the
right middle lobe of the lung.