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Murry, C.E., Soonpaa, M.H., Reinecke, H., Nakajima, H., Nakajima, H.O., Rubart, M., Pasumarthi, K.B.S., Virag, J.I., Bartelmez, S.H., Poppa, V., Bradford, G., Dowell, J.D., Williams, D.A. and Field, L.J. (2004) Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature, 428, 664-668. doi:10.1038/nature02446

has been cited by the following article:

• TITLE: Hematopoietic stem cells are a critical sub-population of whole bone marrow in the treatment of myocardial infarction

  AUTHORS: Philip Davy, Brienne Walker, Livingston Wong, Richard Allsopp

  KEYWORDS: Hematopoietic Stem Cells; Myocardial Infarction; Transplantation; Cardiac Disease

  JOURNAL NAME: Stem Cell Discovery, Vol.3 No.2, April 23, 2013

  ABSTRACT: Recent studies suggest that whole bone marrow (WBM) derived stem cells may facilitate recovery following myocardial infarction. However, the sub-population of WBM responsible for recovery remains uncertain. By adjusting the abundance of CD34+LinNeg cells in human bone marrow we examined the relative significance of hematopoietic stem cells (HSC) in the recovery of cardiac function in a murine model of induced myocardial infarction. Enrichment of HSC by ~100-fold in WBM transplanted into mice significantly increased recovery of heart function and reduced scar size compared to transplantation of WBM depleted in HSC by ~10-fold (P P P P