TITLE:
Effect of Thermal Treatment of the Hydroxyapatite Powders on the Micropore and Microstructure of Porous Biphasic Calcium Phosphate Composite Granules
AUTHORS:
David S. H. Lee, Yuni Pai, Steve Chang
KEYWORDS:
BCP Composite; Hydroxyapatite; Thermal Treatment; Micropore Structure
JOURNAL NAME:
Journal of Biomaterials and Nanobiotechnology,
Vol.4 No.2,
April
17,
2013
ABSTRACT: The effect of thermal treatment of the
hydroxyapatite powders on the micropore structure of porous biphasic calcium
phosphate (BCP) granules was examined. The porous BCP granules could be
attained through mixing and sintering/fracturing thermally treated 60 wt% hydroxyapatite powders and
calcined 40 wt% β-tricalcium
phosphate powders. The observed Scanning electron microscopy (SEM) morphologies
showed that the density of micropores (0.1 - 2.0 μm) including interconnected
micropores of the porous BCP granules mixed with hydroxyapatite powders
thermally treated at 900°C was significantly improved and the composite particles of porous BCP
granules were homogeneously mixed and distributed. This result indicates that
the particles of hydroxyapatite powders that have a tendency to agglomerate at
a room temperature were well isolated and dispersed through thermal treatment
processing before mixing with calcined β-tricalcium
phosphate powders. The microstructural characterizations such as phase purity
and composition of porous BCP granules were performed and verified by X-ray
diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR) analysis.