Article citationsMore>>

F. J. Tefany, R. Barneston and C. Sta, “lmmunocytochemical Analysis of the Cellular Infiltrate in Primary Regressing and Non-Regressing Malignant Melanoma,” Journal of Investigative Dermatology, Vol. 97, No. 2, 1991, 197-202. doi:10.1111/1523-1747.ep12479662

has been cited by the following article:

• TITLE: Spontaneous Regression of a Histologically Proven Cutaneous Squamous Cell Carcinoma

  AUTHORS: Sweta Sengupta, James Arocho, T. Christopher Windham

  KEYWORDS: Squamous Cell Carcinoma; Spontaneous Remission

  JOURNAL NAME: Journal of Cancer Therapy, Vol.4 No.2, April 15, 2013

  ABSTRACT: Introduction: The rate of squamous cell carcinoma spontaneous regression (SR) remains unknown because incidences are rare and underreported. Case Report: We present a case of a 92-year-old Caucasian female who was found to have a 1 cm lesion on her nose. Pathologic evaluation supported the diagnosis of a moderately-differentiated squamous cell carcinoma. The patient refused treatment and returned with no clinical evidence of disease several months later. The lesion spontaneously regressed without excision. Discussion: Frequency of SR of malignancies has been estimated to occur 1 in 80,000 to 100,000 cases [1]. The biologic mechanisms of SR in malignancies remain unclear. Further investigations into the mechanisms of SR may identify potential treatment strategies for cancer.