TITLE:
Nuclear-Chemical Synthesis of 1,4-Diazine Quaternary Salts
AUTHORS:
Nadezhda E. Shchepina, Viktor V. Avrorin, Gennadii A. Badun
KEYWORDS:
Nucleogenic Phenyl Cations; 1, 4-Diazines; Quaternization; Tritium Labeling
JOURNAL NAME:
Open Journal of Synthesis Theory and Applications,
Vol.2 No.2,
April
9,
2013
ABSTRACT: Ion-molecular reactions of nucleogenic phenyl cations with the nucleophilic centers of 1,4-diazines have been investigated for the first time. Previously unknown tritium labeled N-phenyl quaternary derivatives of pyrazine and quinoxaline, which are potential radioactive biomarkers, have been obtained by nuclear-chemical method.