Article citationsMore>>

O’Bryant, S.E., Xiao, G., Barber, R., Huebinger, R., Wilhelmsen, K., Edwards, M., Graff-Radford, N., Doody, R. and Diaz-Arrastia, R. (2011) A blood-based screening tool for Alzheimer’s disease that spans serum and plasma: Findings from TARC and ADNI. PLOS One, 6, e28092. doi:10.1371/journal.pone.0028092

has been cited by the following article:

• TITLE: Comparison of protein concentrations in serum versus plasma from Alzheimer’s patients

  AUTHORS: Ryan M. Huebinger, Guanghua Xiao, Kirk C. Wilhelmsen, Ramon Diaz-Arrastia, Fan Zhang, Sid E. O'Bryant, Robert C. Barber

  KEYWORDS: Alzheimer’s Disease; Serum Proteins; Plasma Proteins

  JOURNAL NAME: Advances in Alzheimer's Disease, Vol.1 No.3, December 28, 2012

  ABSTRACT: Background: There is great interest in developing blood-based biomarkers for Alzheimer’s disease (AD); however, there is no consensus as to what blood fraction is most appropriate for analyzing particular markers. The current study provides empirical evidence regarding how blood-based proteins vary depending on whether they are assayed in serum or plasma. Methods: Weanalyzed concentrations of 100 proteins in matched samples of serum and plasma from 39 Caucasian AD participants from the Texas Alzheimer’s Research and Care Consortium bymultiplex immunoassay. Results: Concentrations of 40 proteins were highly correlated (r2≥ 0.75) between plasma and serum while the remaining proteins were moderately to weakly correlated (r2