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Schwieters, C.D., Kuszewski, J.J., Tjandra, N. and Clore, G.M. (2003) The Xplor-NIH NMR molecular structure determination package. Journal of Magnetic Resonance, 160, 65-73. doi: 10.1016/S1090-7807(02)00014-9

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• TITLE: Spatial structure of beta-amyloid Aβ1-40 in complex with a biological membrane model

  AUTHORS: Konstantin S. Usachev, Andrey V. Filippov, Oleg N. Antzutkin, Vladimir V. Klochkov

  KEYWORDS: 1H NMR; Two-Dimensional NMR (TOCSY, NOESY) Spectroscopy; Alzheimer’s Disease; Beta-Amyloid; Oligopeptides; Micelle

  JOURNAL NAME: Advances in Alzheimer's Disease, Vol.1 No.3, December 21, 2012

  ABSTRACT: The spatial structure of beta-amyloid Aβ1-40 in complex with sodium dodecyl sulfate micelles as a model membrane system was investigated by 1H-1H two-dimensional NMR (TOCSY, NOESY) spectroscopy and molecular dynamic method calculations. On the basis of NOE and chemical shifts changes data, spatial structure of the complex beta-amyloid-model of the cell surface membrane was obtained.