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Andrzejak, R.G., Lehnertz, K., Mormann, F., Rieke, C., David, P. and Elger, C.E. (2001) Indications of nonlinear deterministic and finite-dimensional structures in time series of brain electrical activity: Dependence on re-cording region and brain state. Journal of American Physical Society, 64, 1-8.

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• TITLE: A wavelet-approximate entropy method for epileptic activity detection from EEG and its sub-bands

  AUTHORS: Hamed Vavadi, Ahmad Ayatollahi, Ahmad Mirzaei

  KEYWORDS: Approximate Entropy (ApEn); Wavelet Transform; Epilepsy Detection; EEG Signal; T-Student

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.3 No.12, December 30, 2010

  ABSTRACT: Epilepsy is a common brain disorder that about 1% of world's population suffers from this disorder. EEG signal is summation of brain electrical activities and has a lot of information about brain states and also used in several epilepsy detection methods. In this study, a wavelet-approximate entropy method is ap-plied for epilepsy detection from EEG signal. First wavelet analysis is applied for decomposing the EEG signal to delta, theta, alpha, beta and gamma sub- ands. Then approximate entropy that is a chaotic measure and can be used in estimation complexity of time series applied to EEG and its sub-bands. We used this method for separating 5 group EEG signals (healthy with opened eye, healthy with closed eye, interictal in none focal zone, interictal in focal zone and seizure onset signals). For evaluating separation ability of this method we used t-student statistical analysis. For all pair of groups we have 99.99% separation probability in at least 2 bands of these 6 bands (EEG and its 5 sub-bands). In comparing some groups we have over 99.98% for EEG and all its sub-bands.