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J. J. Tyson and B. Novak, “Regulation of the Eukariotic Cell-Cycle: Molecular Antagonism, Hysteresis, and Irreversible Transitions,” Journal of Theoretical Biology, Vol. 210, No. 2, 2001, pp. 249-263. doi:10.1006/jtbi.2001.2293

has been cited by the following article:

• TITLE: An Optimal Control Problem for Hypoxemic Hypoxia Tissue-Blood Carbon Dioxide Exchange during Physical Activity

  AUTHORS: Jean Marie Ntaganda, Benjamin Mampassi

  KEYWORDS: Arterial Oxygen Pressure; Arterial Dioxide Pressure; Cardiovascular/Respiratory System; Optimal Control Problem; Numerical Simulation

  JOURNAL NAME: Open Journal of Applied Sciences, Vol.3 No.1, March 29, 2013

  ABSTRACT: This paper aims at solving an optimal control problem for determining the response of hypoxia to heart rate and alveolar ventilation that are cardiovascular and respiratory control respectively during a physical activity. A two nonlinear coupled ordinary differential equations is presented. The cost function of optimal control problem is discretized using the linear B-splines functions defined on a regular grid. The results show the determinant parameters stabilized at normal value.