TITLE:
Electrochemical Bioencapsulation of Nanomaterials into Collagen for Biomedical Applications
AUTHORS:
Xingguo Cheng, Vasiliki Poenitzsch, Lauren Cornell, Christopher Tsao, Thomas Potter
KEYWORDS:
Nanomaterials; Electrochemical; Bioencapsulation; Collagen; Biomedical Applications
JOURNAL NAME:
Journal of Encapsulation and Adsorption Sciences,
Vol.3 No.1,
March
29,
2013
ABSTRACT: Here we reported a novel electrochemical encapsulation method to encapsulate various nanomaterials and bimolecules into collagen. The electrochemical encapsulation process involves assembling of collagen along with Nano/bio materials using an isoelectric focusing mechanism. We have showed that a wide range of Nanomaterials such as carbon nanotubes, polymeric nanoparticles, magnetic calcium phosphate nanoparticlesand biomolecules can be encapsulated into collagen. These novel collagen-based composite materials possess improved electric, mechanical, antimicrobial, magnetic, bioactive properties. Thus, this novel electrochemical encapsulation process offers a means to fabricate novel biomaterials for various biomedical applications such as tendon/ligament, nerve, skin tissue engineering, tendon/ligament to bone grafts, and sutures, etc.