TITLE:
Bacteriophages in Escherichia coli antimicrobial resistance
AUTHORS:
Archana Iyer, Elie Barbour, Esam Azhar, Ishtiaq Qadri, Adeel Chaudhary, Adel Abuzenadah, Taha Kumosani, Ghazi Damanhouri, Suhad Bahijri, Ahmed Al-Hejin, Afif M. Abdel Nour, Steve Harakeh
KEYWORDS:
Bacteriophages; Escherischia coli; Antimicrobial Resistance
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.4 No.3A,
March
29,
2013
ABSTRACT: The
continuous battle between humans and the multitude of pathogenic
microorganisms in the environment has sought relief in the form of antimicrobials.
But the counter attack by pathogenic organisms in the form of multidrug
resistance, acquired by various mechanisms such as transformation, transposition,
conjugation and transduction is a major reason for concern. Bacteriophages have
contributed in a significant way to dissemination of genes encoding antimicrobial
resistance, heavy metal resistance and virulence factors through the
phenomenon of transduction. This review aims at compiling information about
the different mechanisms by which bacteriophages aid in transferring genes
involved in antimicrobial resistance to Escherischia coli in various
environments.