TITLE:
Is triglyceride to high-density lipoprotein cholesterol ratio a surrogates for insulin resistance in youth?
AUTHORS:
Antônio C. Oliveira, Ana M. Oliveira, Nelson Oliveira, Atila Oliveira, Marcele Almeida, Lorena M. Veneza, Ana Luisa Oliveira, Luis Adan, Ana M. Ladeia
KEYWORDS:
Insulin Resistance; TG/HDL-C Ratio; Childhood Obesity; Metabolic Disease
JOURNAL NAME:
Health,
Vol.5 No.3,
March
29,
2013
ABSTRACT: As elevated triglyceride (TG) to high-density
lipoprotein cholesterol (HDL-C) ratio has been described as predictor for
cardio metabolic disease with insulin resistance (IR) in the background,
the aim was to assess the relationship between this ratio and IR in youth. Oral glucose tolerance test
was performed in 318 Brazilian students (175 girls, 11.2 ± 3.2 years,
BMI_z-score 1.2 ± 1.4 SD). Measurements: BMI, waist circumference (WC), blood
pressure (BP), lipids, insulin and high
sensitivity Creactive protein (hsCRP). Excessive weight and abdominal
obesity were defined using BMI_z-score and WC and IR by Homeostasis model assessment-insulin
resistance (HOMA-IR). TG/HDL-C
median was 2.37. There was an association between TG/ HDL-C and WC, systolic
and diastolic BP, insulin, HOMA-IR, hsCRP, (p