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Gagliano, N., Dalle, D.I., Torri, C., Migliori, M., Grizzi, F., Milzani, A., Filippi, C., Annoni, G., Colombo, P., Costa, F., Cava, G.G., Bertelli, A.A.E., Giovannini, L. and Gioia, M. (2006) Early cytotoxic effects of Ochratoxin A in rat liver: A morphological, biochemical and molecular study. Toxicology, 225, 214-224. doi:10.1016/j.tox.2006.06.004

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• TITLE: Investigation of the serum oxidative stress in broilers fed on diets supplemented with nickel chloride

  AUTHORS: Bangyuan Wu, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Jianying Huang

  KEYWORDS: Broiler; Nickel Chloride; Oxidative Stress; Serum

  JOURNAL NAME: Health, Vol.5 No.3, March 28, 2013

  ABSTRACT: The purpose of this study was to investigate the serum oxidative stress induced by dietary nickel chloride (NiCl2) in broilers. A total of 240 one-day-old avian broilers were divided into four groups and fed on a cornsoybean basal diet as control diet or the same basal diet supplemented with 300 mg/kg, 600 mg/kg and 900 mg/kg NiCl2. During the experimental period of 42 days, oxidative stress parameters were determined for both control and experimental groups. The results showed that malondialdehyde (MDA) content was significantly higher (p 2 in excess of 300 mg/kg could cause oxidative stress, which could finally impaired the antioxidant function in broilers.