TITLE:
Biomarkers in Acute Kidney Injury
AUTHORS:
Cai-Mei Zheng, Min-Tser Liao, Mei-Yu Lin, Lan Lo, Chia-Chao Wu, Yung-Ho Hsu, Yuh-Feng Lin, Kuo-Cheng Lu
KEYWORDS:
Acute Kidney Injury; Critical Care Centers; Biomarkers; Renal Replacement Therapy
JOURNAL NAME:
Open Journal of Nephrology,
Vol.3 No.1,
March
28,
2013
ABSTRACT: Acute kidney injury (AKI) is one of the popular topics of discussions due to increasing development of biomarkers recently. The disease progression and prognosis may be determined by these biomarkers detected in blood and urine specimens. Since acute kidney injury is associated with a broad spectrum of disease conditions, prevention and early detection of AKI becomes very important in those clinical settings. Early measurements of AKI biomarkers predict subsequent development of intrinsic AKI, dialysis requirement, duration of intensive care unit stay and finally affect mortality. We, here, discuss the acute kidney injury in different clinical situations and associated natures of biomarkers, which may help us guide to prevent and treat AKI more effectively.