Article citationsMore>>

Fukui, M., Mori, Y., Tsujimoto, S., Takehana, K., Sakamoto, N., Kishimoto, N., Imada, T., Maeba, H., Nose, A., Yamahara, H., Kijima, Y., Kitamura, T., Ueyama, T., Kikuchi, S., Tokoro, T., Masaki, H., Nishikawa, M. and Iwasaka, T. (2006) “Takotsubo” cardiomyopathy in a maintenance hemodialysis patient. Therapeutic Apheresis and Dialysis, 10, 94-100. doi:10.1111/j.1744-9987.2006.00308.x

has been cited by the following article:

• TITLE: Gadolinium enhanced MRI in patients with left ventricular apical ballooning syndrome implicates myocarditis as an etiology

  AUTHORS: Andrew O. Maree, Christian Witzke, Godtfred Holmvang, Gregory D. Lewis, Hani Jneid, Lindsay B. Reardon, Nadeem Afridi, Marc J. Semigran, G. William Dec, Harry C. Lowe, Igor F. Palacios

  KEYWORDS: Left Ventricular Apical Ballooning Syndrome; Gadolinium-Enhanced Cardiac Magnetic Resonance Imaging; Myocarditis; Catecholamine

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.3 No.1A, March 26, 2013

  ABSTRACT: Aims: Left ventricular apical ballooning syndrome (LVABS) is a clinical condition of unknown etiology, characterized by acute onset of atypical apical wall motion and absence of coronary artery disease. Gadolinium-enhanced cardiac magnetic resonance imaging (Gd-MRI) may be used to identify patients with myocarditis. Using cardiac MRI, we evaluated whether acute myocarditis may be an etiology that underlies LVABS. Methods and Results: Consecutive patients who presented with LVABS during a three-year period were included. Demographic data was recorded and echocardiography, coronary angiography, and hemodynamic assessment performed. Gd-MRI was performed in all patients. The study was deemed consistent with myocarditis when global myocardial to skeletal muscle enhancement ratio was ≥3.5. Regional Gd-MRI analysis was also performed. Patients (n = 11) were female (100%) and of mean age 72 years (72 ± 11). Preceding febrile illness occurred in 4 (36.3%) and leukocytosis in 6 (54.4%) patients. Initial mean left ventricular ejection fraction (41% ± 12%) improved (70.2% ± 8%) upon follow-up (39 ± 43 days). Global MRI analysis was positive in 5/11 (45.5%) (mean relative enhancement ratio 4.8 ± 1.4). Regional MRI analysis was positive in 4/6 further patients (overall: 9/11 (82%)). Conclusions: Gadolinium enhanced MRI imaging in LVABS implicates myocarditis as a possible etiology. Regional MRI analysis adds sensitivity to global cardiac MRI evaluation.