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S. Bhalla, et al., “PCI-24781 Induces Caspase and Reactive Oxygen Species-Dependent Apoptosis through NFkappaB Mechanisms and Is Synergistic with Bortezomib in Lymphoma Cells,” Clinical Cancer Research, Vol. 15, No. 10, 2009, pp. 3354-3365. doi:10.1158/1078-0432.CCR-08-2365

has been cited by the following article:

• TITLE: Emerging Frontiers in Therapeutics of Diffuse Large B Cell Lymphoma: Epigenetics and B Cell Receptor Signaling

  AUTHORS: Soham Puvvada, Lisa Rimsza

  KEYWORDS: BCR Signaling; Epigenetics

  JOURNAL NAME: Journal of Cancer Therapy, Vol.4 No.3A, March 25, 2013

  ABSTRACT: This review discusses the impact of gene expression profiling and sequencing discoveries on new therapeutic strategies in Non-Hodgkin Lymphomas, particularly Diffuse Large B cell Lymphoma. Alterations in oncogenes, over-active signaling pathways down-stream of the B cell receptor, and epigenetic gene mutations will be described. We will also review new targeting strategies aimed at each of these aspects of cell biology encompassing BCL2, BTK, PKCβ, PI3K/mTOR and HDAC inhibition. Specific new drugs in clinical trials and early trial results are included as well.