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Van Cann, E.M., Slootweg, P.J., de Wilde, P.C., OtteH?ller, I., Koole, R., Stoelinga, P.J. and Merkx, M.A. (2009) The prediction of mandibular invasion by squamous cell carcinomas with the expression of osteoclast-related cytokines in biopsy specimens. International Journal of Oral and Maxillofacial Surgery, 38, 279-284. doi:10.1016/j.ijom.2009.01.005

has been cited by the following article:

• TITLE: Resorption of impacted teeth as a marker of squamous cell carcinoma infiltrating the mandible

  AUTHORS: Sathesh Balasundram, Nicolas Dulguerov, Donald Murray Walker, Colin Liew

  KEYWORDS: Squamous Cell Carcinoma; Invasion; Tooth Resorption

  JOURNAL NAME: Open Journal of Stomatology, Vol.3 No.1, March 18, 2013

  ABSTRACT: Theinvasionofthemandiblebyoralsquamouscellcarcinomahasbeenfirmlydemonstratedbyanatomicalandhistologicalstudies.Althoughsquamouscellcarcinomasmayinduceresorptionoftherootsofstandingteeth,therehavebeennoreportsofthemalsocausingresorptionofthecrownsofteeth. A73-year-oldpatientpresentedwithaninvadingbuccalsquamouscellcarcinoma. Radiologicalinvestigationsshowedtumourinvasionofthedentateregionoftheleftmandibleandresorptionofthecrownsofrightandleftmandibularimpactedthirdmolars. Thepatientunderwentaleftsegmentalmandibulectomyandhistopathologicalexaminationoftheresectedspecimenrevealedresorptionoftheenamelanddentineofanuneruptedimpactedthirdmolarcloselyassociatedwiththeinfiltratingtumour. Thusinfiltratingcarcinomasmayrarelycauseresorptionofthecrownsaswellastherootsofuneruptedteethandcanbeavaluablemarkeroftheextentofspreadofatumourfortheplanningofcompletesurgicalresection. Thesedentalchangesmustbedistinguishedradiologicallyfromidiopathicchangesinuneruptedteethintheabsenceofmalignancy.